CBB752/CPSC452/CPSC752/MBB452/MBB752/MCDB452/MCDB752

http://www.gersteinlab.org/courses/452/

Course description

Genomics describes the determination of the nucleotide sequence as well as many further analyses used to discover functional and structural gene information on all the genes of an organism. Topics include the methods and results of analysis on a genome-wide scale as well as a discussion of the implications of this research. Bioinformatics describes the computational analysis of gene sequences and protein structures on a large scale. Topics include sequence alignment, biological database design, geometric analysis of protein structure, and macromolecular simulation.

Examinations

One midterm exam (covering lectures from September 6 - October 16 and a take-home final exam/project (covering lectures from October 25 - December 6).

Literature discussion section

One session of 60 minutes per week, time to be arranged. Student presentations of recent research papers relevant to the topics of the course. Led by Kevin Keating (328 Bass, 432-6370; kevin.keating@yale.edu) and Jiang Du (204 AKW, 432-1209; jiang.du@yale.edu).

Grades

80% exams, 20% discussion section.